American Airlines, Delta Airlines, Southwest Airlines, JetBlue, United Airlines, and Silver Airways fly directly to Eleuthera ELH which is 45 minutes north of Cayo Loco and GHB which is 5 minutes north of Cayo Loco.

Direct flights from FXE near Fort Lauderdale on Aztec Airways into GHB which is 5 minutes from Cayo Loco!

All major airlines fly to Nassau NAS and then it is a short hop over into GHB on either Pineapple Air or Bahamasair, or Western Air into ELH.